| Through Week 13 of 2024 Season | Single | Single | ||||||||
| Game | Game | |||||||||
| Rushing | Rushing | |||||||||
| Rank | Name | Year | Opponent | Attempts | Rank | Name | Year | Opponent | Yards | |
| 1 | Ty Parks | 2003 | Coldwater | 50 | 1 | Ty Parks | 2003 | New Bremen | 302 | |
| 2 | Jared Huelsman | 2017 | Norwalk St. Paul | 43 | 2 | Jared Huelsman | 2017 | Norwalk St. Paul | 278 | |
| 3 | Alex Schmitmeyer | 2019 | Marion Local | 41 | 3 | Alex Schmitmeyer | 2019 | Fort Recovery | 263 | |
| 4 | Ty Parks | 2004 | Versailles | 38 | 4 | Bryce Schmiesing | 2016 | New Bremen | 257 | |
| 5 | Corky Poeppelman | 1972 | Riverside | 37 | 5 | Ty Parks | 2002 | Lima Central Catholic | 255 | |
| 6 | Brian Wolf | 1991 | Sidney Lehman | 36 | 6 | Bryce Schmiesing | 2016 | Lehman Catholic | 248 | |
| 7 | Alex Schmitmeyer | 2019 | Covington | 35 | 7 | Korey Schultz | 2012 | New Bremen | 239 | |
| 8 | Ty Parks | 2004 | Spencerville | 34 | 8 | Ty Parks | 2003 | Coldwater | 234 | |
| Jared Huelsman | 2017 | Anna | 34 | 9 | Ken Meyer | 1968 | Waynesfield-Goshen | 231 | ||
| 10 | Jeff Stucke | 1989 | St. Henry | 33 | 10 | Ed Garmann | 1952 | Maria Stein | 230 | |
| Jeff Stucke | 1990 | Ansonia | 33 | 11 | Ty Parks | 2004 | Spencerville | 226 | ||
| Alex Schmitmeyer | 2019 | Fort Recovery | 33 | 12 | Ty Parks | 2002 | Marion Local | 222 | ||
| 13 | Brian Wolf | 1991 | St. Henry | 32 | 13 | Jared Huelsman | 2017 | Cuyahoga Heights | 221 | |
| Johnny Nixon | 2020 | Allen East | 32 | 14 | Corky Poeppelman | 1972 | Riverside | 216 | ||
| 15 | Corky Poeppelman | 1972 | New Bremen | 31 | 15 | Ty Parks | 2004 | Versailles | 215 | |
| Jeff Stucke | 1989 | Marion Local | 31 | 16 | Jim Botkin | 1966 | Marion Local | 214 | ||
| Josh Clune | 1995 | Parkway | 31 | 17 | Michael McVety | 2005 | Fort Loramie | 212 | ||
| Ty Parks | 2002 | Coldwater | 31 | 18 | Jared Huelsman | 2016 | Fort Loramie | 211 | ||
| Jared Huelsman | 2016 | Versailles | 31 | 19 | Ty Parks | 2004 | Fort Recovery | 210 | ||
| Jared Huelsman | 2017 | Cuyahoga Heights | 31 | 20 | Sam Dues | 2013 | New Bremen | 209 | ||
| 21 | Ty Parks | 2004 | Delphos St. Johns | 30 | Evan Huelsman | 2015 | Delphos St. Johns | 209 | ||
| Evan Huelsman | 2014 | Parkway | 30 | 22 | Ken Meyer | 1968 | Bradford | 208 | ||
| Jared Huelsman | 2016 | Fort Loramie | 30 | 23 | Josh Clune | 1995 | Parkway | 207 | ||
| Brogan Stephey | 2021 | New Bremen | 30 | 24 | Connor Schmiesing | 2022 | Fort Recovery | 206 | ||
| 25 | Jamie Wolf | 1988 | Marion Local | 29 | 25 | Bryce Schmiesing | 2016 | Lehman Catholic | 201 | |
| Jamie Wolf | 1988 | Dayton Jefferson | 29 | 26 | Brian Homan | 1998 | Parkway | 198 | ||
| Brian Homan | 1998 | Sidney Lehman | 29 | 27 | Brogan Stephey | 2023 | Fort Loramie | 197 | ||
| Andy Roetgerman | 2001 | Coldwater | 29 | 28 | Evan Huelsman | 2014 | West Liberty-Salem | 195 | ||
| Evan Huelsman | 2015 | Fort Loramie | 29 | 29 | John Horstman | 1954 | Ansonia | 192 | ||
| Brogan Stephey | 2024 | St. Henry | 29 | Dave Bergman | 1995 | Toledo Libbey | 192 | |||
| 31 | Tony Brown | 1974 | St. Henry | 28 | Ty Parks | 2002 | Parkway | 192 | ||
| Jamie Wolf | 1987 | New Bremen | 28 | 32 | Broc Miller | 2018 | Parkway | 190 | ||
| Josh Clune | 1994 | Marion Local | 28 | 33 | Korey Schultz | 2012 | Parkway | 188 | ||
| Brian Homan | 1998 | Parkway | 28 | Brogan Stephey | 2024 | Fort Loramie | 188 | |||
| Ty Parks | 2002 | St. Henry | 28 | 35 | Korey Schultz | 2011 | Springfield Catholic | 186 | ||
| Ty Parks | 2004 | Lima Central Catholic | 28 | Alex Schmitmeyer | 2019 | Marion Local | 186 | |||
| Ty Whitford | 2008 | New Bremen | 28 | 37 | Brad Hausfeld | 1971 | Bradford | 185 | ||
| Jared Huelsman | 2016 | Coldwater | 28 | Roy Brown | 1977 | New Bremen | 185 | |||
| Alex Schmitmeyer | 2018 | Marion Local | 28 | 39 | Jacob Niemeyer | 2019 | Versailles | 184 | ||
| 40 | Jim Botkin | 1966 | Marion Local | 27 | 40 | Ty Whitford | 2008 | Delphos St. Johns | 183 | |
| Shawn Sharp | 1985 | St. Henry | 27 | 41 | Jared Huelsman | 2016 | Versailles | 181 | ||
| Jeff Stucke | 1989 | Coldwater | 27 | 42 | Ken Meyer | 1968 | Parkway | 180 | ||
| Jeff Stucke | 1990 | New Bremen | 27 | 43 | Brogan Stephey | 2022 | Fort Recovery | 179 | ||
| Jason Stucke | 1992 | Milan Edison | 27 | 44 | Rick Albers | 1983 | Parkway | 178 | ||
| Josh Clune | 1994 | Parkway | 27 | 45 | Korey Schultz | 2012 | Fort Recovery | 176 | ||
| Dave Bergman | 1995 | Toledo Libbey | 27 | 46 | Ron Boeke | 1975 | Tipp City Bethel | 175 | ||
| Ty Parks | 2002 | Marion Local | 27 | Toby Meyer | 1988 | Coldwater | 175 | |||
| Ty Parks | 2002 | Lima Central Catholic | 27 | Ty Parks | 2002 | Coldwater | 175 | |||
| Evan Huelsman | 2015 | Delphos St. Johns | 27 | 49 | Jon Meyer | 1971 | Waynesfield-Goshen | 174 | ||
| Jared Huelsman | 2017 | Delphos St. Johns | 27 | Ty Whitford | 2009 | Springfield Catholic | 174 | |||